When you add the "Registration" add-on to your calendar, you can send 3 types of emails to your users after activating registration on the event. You can manage it by clicking on each, right next to the "Registration" button. 
Confirmation Email:
Here you can add a subject and text of actual message you want to send to your users.
Reminder Email:
Besides the message you want to send to your users, you can also set a reminder to send them before the event. You are to choose the time you want to remind them before the event starts.
Cancelation Email:
If somehow your event is cancelled, you can warn about that to your users as well.
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